Substance
ID:348278
Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide
Names and Identifiers
IUPAC Traditional name
N-{3-[(4-{[3-(trifluoromethyl)phenyl]amino}pyrimidin-2-yl)amino]phenyl}cyclopropanecarboxamide
IUPAC name
N-{3-[(4-{[3-(trifluoromethyl)phenyl]amino}pyrimidin-2-yl)amino]phenyl}cyclopropanecarboxamide
Synonyms
Aurora Kinase Inhibitor IIICyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide
Properties
Physical Property
Solubility
DMSO: >7 mg/mL
H2O: <2 mg/mL
Apperance
white solid
Safety Information
Product Information
Purity
≥98% (HPLC)
Empirical Formula (Hill Notation)
C21H18F3N5O
Molecule Details
Biochem/physiol Actions
ATP-competitive Aurora A kinase inhibitor with IC50 = 42 nM
ATP-competitive Aurora A kinase inhibitor with IC50 = 42 nM
Molecular Spectra
No Data Available
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References
No Data Available
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