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Substance
ID:347509
Structure
Similarity
Functional Group
Text
ID:4252
γ-Butyrolactone
Sigma Aldrich
ID: H7629
Names and Identifiers
IUPAC name
oxolan-2-one
Synonyms
GBL
γ-羟基丁酸内酯
γ-Butyrolactone
γ-丁内酯
4-羟基丁酸内酯
γ-Hydroxybutyric acid lactone
4-Hydroxybutyric acid lactone
IUPAC Traditional name
butyrolactone
Registration numbers
CAS Number
96-48-0
Beilstein Number
105248
EC Number
202-509-5
MDL Number
MFCD00005386
Properties
Physical Property
Flash Point
98 °C
208.4 °F
Vapor Density
3 (vs air)
Melting Point
-45 °C(lit.)
Refractive Index
n20/D 1.436(lit.)
Density
1.12 g/mL at 25 °C(lit.)
Boiling Point
204-205 °C(lit.)
Auto Ignition Point
851 °F
Vapor Pressure
1.5 mmHg ( 20 °C)
Safety Information
Explode Limits
16 %
GHS Hazard statements
H302
-
H318
-
H336
European Hazard Symbols
Harmful (Xn)
Personal Protective Equipment
Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Safety Statements
26
-
39
German water hazard class
1
GHS Precautionary statements
P261
-
P280
-
P305+P351+P338
Risk Statements
22
-
41
-
67
RTECS
LU3500000
GHS Pictograms
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Signal Word
Danger
Storage Temperature
2-8°C
MSDS Link
Download link
Product Information
Purity
≥99% (GC)
Empirical Formula (Hill Notation)
C4H6O2
Molecule Details
Biochem/physiol Actions
Precursor of γ-hydroxybutyric acid (GHB). It blocks dopamine release by blocking impulse flow in dopaminergic neurons. Pretreatment with γ-butyrolactone allows detection of autoreceptor-induced dopamine release.
Molecular Spectra
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References
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