Substance
ID:347002
Names and Identifiers
IUPAC name
5-(4-methylbenzoyl)-3-nitrobenzene-1,2-diol
Synonyms
Tolcapone3,4-Dihydroxy-4′-methyl-5-nitrobenzophenoneRo 40-7592
IUPAC Traditional name
tolcapone (product)
Properties
Safety Information
Product Information
Purity
≥98% (HPLC)
Empirical Formula (Hill Notation)
C14H11NO5
Physical Property
Apperance
yellow powder
Solubility
DMSO: ≥15 mg/mL
Molecule Details
Biochem/physiol Actions
Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor. It inhibits both central and peripheral COMT. Tolcapone crosses the blood-brain barrier, and has been used for L-DOPA adjunct therapy in the treatment of Parkinson′s Disease.
Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor. It inhibits both central and peripheral COMT. Tolcapone crosses the blood-brain barrier, and has been used for L-DOPA adjunct therapy in the treatment of Parkinson′s Disease.
Molecular Spectra
No Data Available
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References
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