Substance
ID:346988
Names and Identifiers
IUPAC Traditional name
fluocinonide
Synonyms
Lonide(6α,11β,16α)-21-(acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dioneFluocinonide
IUPAC name
2-[(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl acetate
Properties
Safety Information
MSDS Link
Storage Temperature
2-8°C
Physical Property
Solubility
DMSO: ≥19 mg/mL
Optical Rotation
[α]/D +75 to +90°, c = 1 in dichloromethane
Apperance
white to tan powder
Product Information
Purity
≥98% (HPLC)
Empirical Formula (Hill Notation)
C26H32F2O7
Molecule Details
Biochem/physiol Actions
Flucinonide is a fluorinated glucocorticid that is used as a topical anti-inflammatory agent. Recently, flucinonide and other fluorinated glucocorticolids were identified as smoothend agonists. Flucinonide induces expression of Gli-reporter luciferase in Shh-LIGHT2 cells.
Flucinonide is a fluorinated glucocorticid that is used as a topical anti-inflammatory agent. Recently, flucinonide and other fluorinated glucocorticolids were identified as smoothend agonists. Flucinonide induces expression of Gli-reporter luciferase in Shh-LIGHT2 cells.
Molecular Spectra
No Data Available
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References
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