Substance
ID:346938
Names and Identifiers
IUPAC name
4-(2-{[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol
IUPAC Traditional name
4-(2-{[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol
Synonyms
ZM 2413854-(-2-[7-amino-2-{2-furyl}{1,2,4}triazolo{2,3-a} {1,3,5}triazin-5-yl-amino]ethyl)phenol
Properties
Physical Property
Solubility
DMSO: >15 mg/mL
Apperance
white to tan powder
Safety Information
MSDS Link
Safety Statements
46
GHS Hazard statements
H301
European Hazard Symbols
Toxic (T)GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Signal Word
Danger
Risk Statements
25
GHS Precautionary statements
P301+P310
German water hazard class
3
Storage Temperature
room temp
Product Information
Purity
≥98% (HPLC)
Empirical Formula (Hill Notation)
C16H15N7O2
Molecule Details
Biochem/physiol Actions
ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.
ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.
Molecular Spectra
No Data Available
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References
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