Substance

ID:346898

β-Glycerophosphate disodium salt hydrate

Names and Identifiers
Synonyms
β-甘油磷酸 二钠盐 水合物BGP甘油-2-磷酸 二钠盐 水合物β-Glycerophosphate disodium salt hydrateGlycerol 2-phosphate disodium salt hydrate
IUPAC name
disodium 2-(phosphonatooxy)propane-1,3-diol hydrate
IUPAC Traditional name
disodium glycerol 2-phosphate hydrate
Registration numbers
CAS Number
EC Number
MDL Number
Properties
Safety Information
RTECS
UA0600000
German water hazard class
3
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
MSDS Link
Product Information
Linear Formula
(HOCH2)2CHOP(O)(ONa)2 · xH2O
Impurities
≤1.0 mol % L-α-isomer
≤0.1% Inorganic phosphorus
Biological Source
from synthetic
Physical Property
Melting Point
102-104 °C(lit.)
Molecule Details
Quality
Low inorganic phosphate content. Mixtures of α- and β-glycerophosphate have historically been used in microbiological media but high levels of inorganic (free) phosphate has been associated with the irregular growth of bacteria and unwanted precipitates.9
Application
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.1 BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition.2,3 It functions as an organic phosphate donor4 and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells.5,6 BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.7,8
β-glycerophosphate is used in homegenization solutions for muscles extracts following fixation.
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.
Molecular Spectra
No Data Available
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References
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