Substance
ID:346749
Names and Identifiers
IUPAC name
2-methyl-1-[2-(propan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one
Synonyms
3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridineKC-4042-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl] 1-propanoneIbudilast
IUPAC Traditional name
ibudilast
Properties
Physical Property
Solubility
H2O: soluble4.5 mg/mL
DMSO: soluble28 mg/mL
Apperance
white solid
Safety Information
Risk Statements
22-36/37/38
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Hazard statements
H302-H315-H319-H335
European Hazard Symbols
Harmful (Xn)GHS Signal Word
Warning
GHS Precautionary statements
P261-P305+P351+P338
RTECS
UR0711200
Safety Statements
26-36
MSDS Link
German water hazard class
3
Storage Temperature
2-8°C
Product Information
Empirical Formula (Hill Notation)
C14 H18 N2 O
Purity
≥99% (HPLC)
Pharmacology Properties
Gene Information
human ... PDE4A(5141), PDE4B(5142), PDE4C(5143), PDE4D(5144)
Molecule Details
Biochem/physiol Actions
Phosphodiesterase IV (PDE4) inhbitor. Inhibits platelet aggregation. Anti-asthma drug.
Phosphodiesterase IV (PDE4) inhbitor. Inhibits platelet aggregation. Anti-asthma drug.
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data