Substance

ID:346

Names and Identifiers
Brand Name
EndiemalumMetarbital [INN-Spanish]Metarbitale [Dcit]MetharbitoneGemonalMetharbutalMetabarbitalMethabarbitalMethabarbitoneMetharbital [INN:Jan]Metharbitalum [INN-Latin]MethylbarbitalGemonilGemonitN-MethylbarbitalEndiemal
IUPAC Traditional name
metharbital
IUPAC name
5,5-diethyl-1-methyl-1,3-diazinane-2,4,6-trione
Synonyms
Metharbital
Registration numbers
CAS Number
PubChem SID
PubChem CID
Properties
Physical Property
Hydrophobicity(logP)
0.6
Solubility
1980 mg/L
Molecule Details
Drug Groups
approved
Description
Metharbital was patented in 1905 by Emil Fischer working for Merck. It was marketed as Gemonil by Abbott Laboratories. It is a barbiturate anticonvulsant, used in the treatment of epilepsy. It has similar properties to phenobarbital.

Indication
Metharbital is used for the treatment of epilepsy.
Pharmacology
Metharbital, a barbiturate, is used for the treatment of short term insomnia. It belongs to a group of medicines called central nervous system (CNS) depressants that induce drowsiness and relieve tension or nervousness. Little analgesia is conferred by barbiturates; their use in the presence of pain may result in excitation.
Toxicity
Signs of overdose include confusion (severe), decrease in or loss of reflexes, drowsiness (severe), fever, irritability (continuing), low body temperature, poor judgment, shortness of breath or slow or troubled breathing, slow heartbeat, slurred speech, staggering, trouble in sleeping, unusual movements of the eyes, weakness (severe).
Affected Organisms
Humans and other mammals
External Links
Molecular Spectra
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References
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