Substance
ID:345354
Names and Identifiers
IUPAC name
(S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol
IUPAC Traditional name
quinidine
Synonyms
Quinidine奎尼丁
Registration numbers
CAS Number
EC Number
PubChem SID
Beilstein Number
MDL Number
Properties
Product Information
Impurities
≤2% water
~10% hydroquinidine (HPLC)
Empirical Formula (Hill Notation)
C20H24N2O2
Purity
≥98.0% (dried material, NT)
Quality
crystallized
Safety Information
GHS Signal Word
Danger
European Hazard Symbols
Harmful (Xn)GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
MSDS Link
GHS Hazard statements
H301
UN Number
2811
RID/ADR
UN 2811 6.1/PG 3
Packing Group
3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Safety Statements
36
Risk Statements
22
Hazard Class
6.1
GHS Precautionary statements
P301+P310
RTECS
VA4725000
German water hazard class
3
Pharmacology Properties
Gene Information
human ... ABCB1(5243), CYP2D6(1565), CYP3A4(1576), KCNH1(3756)mouse ... Abcb1a(18671), Abcb1b(18669)rat ... Cyp2d1(266684), Cyp2d2(25053), Cyp2d3(24303), Cyp2d4v1(171522)
Physical Property
Optical Rotation
[α]20/D +265±5°, c = 0.8% in ethanol (dry matter)
Melting Point
168-172 °C(lit.)
Molecule Details
Biochem/physiol Actions
Class IA antiarrhythmic; potassium channel blocker.
Other Notes
Chiral catalyst, used e.g. in highly enantioselective [2+2] cycloadditions1,2,3
Packaging
10, 50 g in poly bottle
Class IA antiarrhythmic; potassium channel blocker.
Other Notes
Chiral catalyst, used e.g. in highly enantioselective [2+2] cycloadditions1,2,3
Packaging
10, 50 g in poly bottle
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data