Substance

ID:345261

O-tert-Butylhydroxylamine hydrochloride

Names and Identifiers
IUPAC name
O-tert-butylhydroxylamine hydrochloride
IUPAC Traditional name
O-tert-butylhydroxylamine hydrochloride
Synonyms
O-(1,1-Dimethylethyl)hydroxylamine hydrochlorideO-tert-Butylhydroxylamine hydrochloride2-Aminooxy-2-methylpropane hydrochloridetert-Butoxyamine hydrochlorideO-叔丁基羟胺 盐酸盐
Registration numbers
CAS Number
EC Number
Beilstein Number
MDL Number
PubChem SID
Properties
Safety Information
European Hazard Symbols
Flammable Flammable (F)
MSDS Link
RID/ADR
UN 1325 4.1/PG 3
German water hazard class
3
GHS Pictograms
GHS02
Flammable gases, category 1
Flammable aerosols, categories 1,2
Flammable liquids, categories 1,2,3
Self-reactive substances and mixtures, Types B,C,D,E,F
Pyrophoric liquids, category 1
Pyrophoric solids, category 1
Self-heating substances and mixtures
Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3
Organic peroxides, Types B,C,D,E,F
GHS Signal Word
Warning
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Packing Group
3
Risk Statements
11
Hazard Class
4.1
GHS Precautionary statements
P210
UN Number
1325
GHS Hazard statements
H228
Product Information
Purity
≥99.0% (AT)
Linear Formula
(CH3)3CONH2 · HCl
Physical Property
Melting Point
~155 °C (dec.)
Molecule Details
Other Notes
Useful reagent for the preparation of N-tert-butoxyamino acids as substrates for the unambiguous synthesis of N-hydroxy peptides9
Packaging
1, 5 g in glass bottle
Application
Reactant involved in synthesis of biologically active molecules including:
• CGS 25966 derivatives for use as MMP inhibitors1
• Imidazolidinedione derivatives for use as antimalarial treatments2
• Pyrimidine ribonucleotide analogs as P2Y6 receptor agonists3
• Rab proteins for isoprenylation and geranylgeranylation inhibition4Reactant involved in:
• Synthesis of N-(arylethyl)-O-tert-butylhydroxamates for use as Weinreb amide equivalents5
• Double allylic alkylation of indole-2-hydroxamates6
• SN2 substitution reactions at amide nitrogens7
• Photocycloaddition to C=N bonds for synthesis of 1,3-diazepines8
Molecular Spectra
No Data Available
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References
No Data Available
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