Substance

ID:343465

Names and Identifiers
IUPAC Traditional name
hydrocortisone
Synonyms
17-HydroxycorticosteroneCortisol11β,17α,21-Trihydroxypregn-4-ene-3,20-dioneReichstein’s substance M氢化皮质酮Kendall’s compound F氢化可的松4-Pregnene-11β,17α,21-triol-3,20-dione氢化泼尼松龙皮质醇Hydrocortisone11β,17α,21-三羟基孕甾-4-烯-3,20-二酮17-羟基皮质甾酮4-孕烯-11β,17α,21-三醇-3,20-二酮
IUPAC name
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
Registration numbers
EC Number
200-020-1
CAS Number
50-23-7
MDL Number
MFCD00011654
Beilstein Number
1354819
Properties
Safety Information
GHS Precautionary statements
P281
European Hazard Symbols
Harmful Harmful (Xn)
RTECS
GM8925000
GHS Pictograms
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Signal Word
Warning
GHS Hazard statements
H361
MSDS Link
Download link
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Risk Statements
63
Safety Statements
36/37
German water hazard class
3
Physical Property
Melting Point
211-214 °C(lit.)
Optical Rotation
[α]25/D +166°, c = 1 in ethanol
Product Information
Empirical Formula (Hill Notation)
C21H30O5
Purity
98%
Molecule Details
Packaging
5 g in glass bottle
Biochem/physiol Actions
Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency.
Molecular Spectra
No Data Available
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References
No Data Available
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