Substance

ID:341980

Names and Identifiers
IUPAC Traditional name
triamcinolone
IUPAC name
(1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
Synonyms
9α-Fluoro-11β,16α,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dioneTriamcinoloneFluoxyprednisolone
Registration numbers
EC Number
204-718-7
MDL Number
MFCD00010477
CAS Number
124-94-7
PubChem SID
24857272
Properties
Safety Information
GHS Pictograms
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Safety Statements
22-36
European Hazard Symbols
Harmful Harmful (Xn)
German water hazard class
3
GHS Signal Word
Warning
RTECS
TU3850000
MSDS Link
Download link
GHS Precautionary statements
P281
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
40
GHS Hazard statements
H351
Physical Property
Melting Point
262-263 °C(lit.)
Optical Rotation
[α]25/D +69°, c = 2 in DMF
Product Information
Empirical Formula (Hill Notation)
C21H27FO6
Molecule Details
Biochem/physiol Actions
Triamcinolone is a synthetic glucocorticoid agonist; induces gene expression and apoptosis; inhibits prostaglandin synthesis; impairs tumor necrosis factor (TNF)-α-induced degradation of κB-α; potentiates the differentiation-inducing effects of bone morphogenetic proteins (BMP-2, -4, -6).
Packaging
1 g in glass bottle
250 mg in glass bottle
Molecular Spectra
No Data Available
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References
No Data Available
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