Substance
ID:339819
Names and Identifiers
IUPAC name
(2S)-2-(chloromethyl)oxirane
IUPAC Traditional name
(S)-epichlorohydrin
Synonyms
(S)-(+)-Epichlorohydrin(S)-(+)-2-(Chloromethyl)oxirane(S)-(+)-2-(氯甲基)环氧乙烷(S)-(+)-环氧氯丙烷
Registration numbers
MDL Number
Beilstein Number
CAS Number
PubChem SID
Properties
Physical Property
Flash Point
32 °C
89.6 °F
Refractive Index
n20/D 1.438(lit.)
Vapor Pressure
12.5 mmHg ( 20 °C)
Density
1.183 g/mL at 25 °C(lit.)
Optical Rotation
[α]20/D +35°, c = 1 in methanol
Auto Ignition Point
1421 °F
Boiling Point
92-93 °C/360 mmHg(lit.)
Vapor Density
3.2 (vs air)
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Flammable gases, category 1
Flammable aerosols, categories 1,2
Flammable liquids, categories 1,2,3
Self-reactive substances and mixtures, Types B,C,D,E,F
Pyrophoric liquids, category 1
Pyrophoric solids, category 1
Self-heating substances and mixtures
Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3
Organic peroxides, Types B,C,D,E,F
MSDS Link
Safety Statements
53-45
RID/ADR
UN 2023 6.1/PG 2
European Hazard Symbols
Toxic (T)Personal Protective Equipment
Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Risk Statements
45-10-23/24/25-34-43
Explode Limits
21 %
GHS Hazard statements
H226-H301-H311-H314-H317-H331-H350
Hazard Class
6.1
GHS Signal Word
Danger
German water hazard class
3
GHS Precautionary statements
P201-P261-P280-P301+P310-P305+P351+P338-P310
RTECS
RR0427100
UN Number
2023
Packing Group
2
Product Information
Purity
98%
Optical Purity
ee: 97% (GLC)
Empirical Formula (Hill Notation)
C3H5ClO
Molecule Details
Application
Chiral building block in the enantioselective syntheses of hydroxyisoxazolidines1 and (+)-cis-sylvaticin, a potential antitumor agent.2
Used in the total synthesis of Macquarimicins and in the total synthesis of the macrolide RK-397.
Used to synthesize inhibitors of fatty acid oxidation as potential metabolic modulators.
Packaging
5, 25 g in glass bottle
Legal Information
Manufactured under license by Shasun Chemicals and Drugs Limited, using Jacobsen HKR technology.
Chiral building block in the enantioselective syntheses of hydroxyisoxazolidines1 and (+)-cis-sylvaticin, a potential antitumor agent.2
Used in the total synthesis of Macquarimicins and in the total synthesis of the macrolide RK-397.
Used to synthesize inhibitors of fatty acid oxidation as potential metabolic modulators.
Packaging
5, 25 g in glass bottle
Legal Information
Manufactured under license by Shasun Chemicals and Drugs Limited, using Jacobsen HKR technology.
Molecular Spectra
No Data Available
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References
No Data Available
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