Substance
ID:339385
Names and Identifiers
IUPAC name
diethyl (bromodifluoromethyl)phosphonate
IUPAC Traditional name
diethyl bromodifluoromethylphosphonate
Synonyms
Diethyl (bromodifluoromethyl)phosphonate溴氟甲基膦酸二乙酯(Bromodifluoromethyl)phosphonic acid diethyl ester
Properties
Physical Property
Boiling Point
40-41 °C/0.05 mmHg(lit.)
Flash Point
>113 °C
>235.4 °F
Density
1.503 g/mL at 25 °C(lit.)
Refractive Index
n20/D 1.417(lit.)
Product Information
Linear Formula
BrCF2P(O)(OC2H5)2
Purity
96%
Safety Information
Molecule Details
Packaging
5 g in glass bottle
Application
Reactant for:
• Preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3)1
• Synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps2
• P-C bond cleavage on basic hydrolysis3
• Preparation of a prodrug for intracellular delivery of protein tyrosine phosphatase 1B (PTP1B) inhibitor (nonhydrolyzable difluoromethylphosphonate moiety)4
5 g in glass bottle
Application
Reactant for:
• Preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3)1
• Synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps2
• P-C bond cleavage on basic hydrolysis3
• Preparation of a prodrug for intracellular delivery of protein tyrosine phosphatase 1B (PTP1B) inhibitor (nonhydrolyzable difluoromethylphosphonate moiety)4
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data