Substance
ID:336912
Names and Identifiers
IUPAC name
2H,3H,4H,6H,7H,8H,9H,10H-pyrimido[1,2-a]azepine
IUPAC Traditional name
1,8-diazabicycloundec-7-ene
Synonyms
DBU2,3,4,6,7,8,9,10-八氢嘧啶并[1,2-a]氮杂卓1,8-Diazabicyclo[5.4.0]undec-7-ene2,3,4,6,7,8,9,10-Octahydropyrimidol[1,2-a]azepine1,8-二氮杂双环[5.4.0]十一碳-7-烯
Registration numbers
MDL Number
CAS Number
Beilstein Number
EC Number
PubChem SID
Properties
Physical Property
Boiling Point
80-83 °C/0.6 mmHg(lit.)
Density
1.018 g/mL at 25 °C(lit.)
Flash Point
240.8 °F
116 °C
Refractive Index
n20/D 1.522-1.524(lit.)
Vapor Pressure
5.3 mmHg ( 37.7 °C)
Safety Information
GHS Pictograms
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
UN Number
3267
Personal Protective Equipment
Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RID/ADR
UN 3267 8/PG 2
Hazard Class
8
European Hazard Symbols
Corrosive (C)GHS Precautionary statements
P273-P280-P301+P310-P305+P351+P338-P310
Packing Group
2
German water hazard class
2
MSDS Link
Risk Statements
22-34-52/53
Safety Statements
26-36/37/39-45
GHS Signal Word
Danger
GHS Hazard statements
H290-H301-H314-H412
Product Information
Purity
98%
Empirical Formula (Hill Notation)
C9H16N2
Molecule Details
Application
Halogenated Diels-Alder adducts were dehydrohalogenated with this base, and the resulting activated 2,4-dienones were subjected to regio- and stereo-directed Michael additions, using Yamamoto′s reagent (CH3Cu · BF3).2
Used in a new synthesis of the ABCD ring system of Camptothecin.
Features and Benefits
Strong hindered amine base.
Packaging
25, 100, 500 g in glass bottle
Citation
An application review.1
Halogenated Diels-Alder adducts were dehydrohalogenated with this base, and the resulting activated 2,4-dienones were subjected to regio- and stereo-directed Michael additions, using Yamamoto′s reagent (CH3Cu · BF3).2
Used in a new synthesis of the ABCD ring system of Camptothecin.
Features and Benefits
Strong hindered amine base.
Packaging
25, 100, 500 g in glass bottle
Citation
An application review.1
Molecular Spectra
No Data Available
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References
No Data Available
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