Substance
ID:331453
Names and Identifiers
IUPAC Traditional name
1-methylindole-2-carboxylic acid
IUPAC name
1-methyl-1H-indole-2-carboxylic acid
Synonyms
1-甲基吲哚-2-甲酸NSC 683571-Methylindole-2-carboxylic acid
Properties
Safety Information
Risk Statements
22-36/37/38
MSDS Link
European Hazard Symbols
Harmful (Xn)RTECS
NL6012400
German water hazard class
3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Signal Word
Warning
GHS Precautionary statements
P261-P305+P351+P338
Safety Statements
26
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Hazard statements
H302-H315-H319-H335
Physical Property
Melting Point
212-213 °C (dec.)(lit.)
Product Information
Empirical Formula (Hill Notation)
C10H9NO2
Purity
98%
Molecule Details
Packaging
1, 5 g in glass bottle
Application
• Reactant for preparation of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors1
• Reactant for synthesis of fenbufen and ethacrynic acid derivatives as potential antitumor agents via amide coupling reactions2
• Reactant for diastereoselective synthesis of vinylated heterocycles via ruthenium-catalyzed oxidative vinylation with alkenes3
• Reactant for synthesis of 2,3-dihalo indoles via hypervalent iodine mediated decarboxylative halogenation4
• Reactant for preparation of α-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis5
• Reactant for preparation of anthranilic acid mimics as bacterial translation inhibitors6
1, 5 g in glass bottle
Application
• Reactant for preparation of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors1
• Reactant for synthesis of fenbufen and ethacrynic acid derivatives as potential antitumor agents via amide coupling reactions2
• Reactant for diastereoselective synthesis of vinylated heterocycles via ruthenium-catalyzed oxidative vinylation with alkenes3
• Reactant for synthesis of 2,3-dihalo indoles via hypervalent iodine mediated decarboxylative halogenation4
• Reactant for preparation of α-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis5
• Reactant for preparation of anthranilic acid mimics as bacterial translation inhibitors6
Molecular Spectra
No Data Available
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References
No Data Available
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