Substance
ID:326295
Names and Identifiers
IUPAC Traditional name
ethyl 3-(4-fluorophenyl)-3-oxopropanoate
IUPAC name
ethyl 3-(4-fluorophenyl)-3-oxopropanoate
Synonyms
4-Fluoro-β-oxobenzenepropanoic acid ethyl esterEthyl 4-fluorobenzoylacetate对氟苯甲酰乙酸乙酯Ethyl (4-fluorobenzoyl)acetate(4-氟苯甲酰)乙酸乙酯(p-Fluorobenzoyl)acetic acid ethyl esterEthyl 3-(4-fluorophenyl)-3-oxopropionate
Properties
Product Information
Linear Formula
FC6H4COCH2CO2C2H5
Safety Information
Physical Property
Refractive Index
n20/D 1.5040(lit.)
Boiling Point
117-120 °C(lit.)
Density
1.174 g/mL at 25 °C(lit.)
Molecule Details
Packaging
1, 5 g in glass bottle
Application
Reactant used as a precursor in:
• Condensation reactions with diamines via C-C bond cleavage for synthesis of benzimidazoles and perimidines1 for possible use as antimalarial treatments2
• Base-promoted domino Michael addition / cyclization / elimination reactions for synthesis of hydroxybenzophenones3
• Oxidative cross-coupling with indoles via dioxygen activation4
• Cyclization of keto esters for synthesis of pyrones5
• Lewis base catalyzed hydrosilylation for synthesis of α-acetoxy β-amino acid derivatives6
• Conia-ene reactions for synthesis of methylenecyclopentane derivatives7
1, 5 g in glass bottle
Application
Reactant used as a precursor in:
• Condensation reactions with diamines via C-C bond cleavage for synthesis of benzimidazoles and perimidines1 for possible use as antimalarial treatments2
• Base-promoted domino Michael addition / cyclization / elimination reactions for synthesis of hydroxybenzophenones3
• Oxidative cross-coupling with indoles via dioxygen activation4
• Cyclization of keto esters for synthesis of pyrones5
• Lewis base catalyzed hydrosilylation for synthesis of α-acetoxy β-amino acid derivatives6
• Conia-ene reactions for synthesis of methylenecyclopentane derivatives7
Molecular Spectra
No Data Available
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References
No Data Available
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