Substance
ID:324306
Names and Identifiers
IUPAC name
4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
IUPAC Traditional name
4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Synonyms
4,4,5,5-Tetramethyl-2-(pyrazol-4-yl)-1,3,2-dioxaborolane4,4,5,5-四甲基-2-(1H-吡唑-4-基)-1,3,2-二氧杂戊硼烷4-Pyrazoleboronic acid pinacol ester4,4,5,5-Tetramethyl-2-(1H-pyrazol-2-yl)-1,3,2-dioxaborolane4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazolePyrazol-4-ylboronic acid pinacol ester4-吡唑硼酸频哪醇酯4,4,5,5-Tetramethyl-2-(1H-pyrazol-4-yl)-1,3,2-dioxaborolane
Properties
Safety Information
European Hazard Symbols
Irritant (Xi)Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
36/37/38
GHS Precautionary statements
P261-P305+P351+P338
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Signal Word
Warning
MSDS Link
German water hazard class
3
Safety Statements
26-36
GHS Hazard statements
H315-H319-H335
Physical Property
Melting Point
142-146 °C(lit.)
Product Information
Linear Formula
(CH3)4C2O2BC3N2H3
Purity
97%
Molecule Details
Packaging
1, 5, 25 g in glass bottle
Legal Information
Product of Boron Molecular
Application
Reagent used for
• Suzuki-Miyaura cross-couplings1
• Ruthenium-catalyzed asymmetric hydrogenation2 Reagent used in preparation of inhibitors of many highly significant therapeutic enzymes and kinases containing the privileged scaffold pyrazole, including
• VEGF3
• Aurora3,4
• Rho (ROCK)2
• Janus Kinase 2 (JAK)5
• c-MET6
• ALK6
• S-nitrosoglutathione reductase7
• CDC78
• Acetyl-CoA carboxylase9
• Prosurvival Bcl-2 protein10
• Viral RNA-Dependent RNA polymerase11
• Long Chain Fatty Acid Elongase 612
• PI313
• AKT14
• Chk115
• Protein Kinase B16
1, 5, 25 g in glass bottle
Legal Information
Product of Boron Molecular
Application
Reagent used for
• Suzuki-Miyaura cross-couplings1
• Ruthenium-catalyzed asymmetric hydrogenation2 Reagent used in preparation of inhibitors of many highly significant therapeutic enzymes and kinases containing the privileged scaffold pyrazole, including
• VEGF3
• Aurora3,4
• Rho (ROCK)2
• Janus Kinase 2 (JAK)5
• c-MET6
• ALK6
• S-nitrosoglutathione reductase7
• CDC78
• Acetyl-CoA carboxylase9
• Prosurvival Bcl-2 protein10
• Viral RNA-Dependent RNA polymerase11
• Long Chain Fatty Acid Elongase 612
• PI313
• AKT14
• Chk115
• Protein Kinase B16
Molecular Spectra
No Data Available
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References
No Data Available
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