Substance

ID:315532

4-Cyanophenylboronic acid

Names and Identifiers
IUPAC name
(4-cyanophenyl)boronic acid
IUPAC Traditional name
4-cyanophenylboronic acid
Synonyms
4-氰基苯硼酸4-Cyanobenzeneboronic acid4-Cyanophenylboronic acid4-Cyanophenylboric acid(p-Cyanophenyl)boronic acid
Registration numbers
MDL Number
CAS Number
PubChem SID
Properties
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
MSDS Link
German water hazard class
3
Product Information
Linear Formula
NCC6H4B(OH)2
Physical Property
Melting Point
>350 °C(lit.)
Molecule Details
Other Notes
Contains varying amounts of anhydride
Packaging
1 g in glass bottle
10 g in poly bottle
Application
Reactant involved in:
• Oxidative hydroxylation1
• Trifluoromethylation2
• 1,4-Addition reactions3Precursor in the synthesis of inhibitors such as:
• Tpl2 kinase inhibitors4
• P2X7 antagonists used in the treatment of pain5
Reagent used for
• Palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water
• Ruthenium catalyzed direct arylation of benzylic sp3 carbons of acyclic amines with arylboronates
• Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids
• Ferric perchlorate-promoted reaction of fullerenes with various arylboronic acids to give fullerenyl boronic esters
• Phosphine-free Suzuki-Miyaura cross-coupling
• Palladacycles as effective catalysts for multicomponent reaction with allylpalladium-intermediates
• Chan-Lam-type Cu-catalyzed S-arylation of thiols
• Regioselective cross-coupling reactions under modfied Suzuki and Still cross-coupling reactions with Copper catalysis
• Metal-free biaryl coupling in dimethyl carbonate as a solventReagent used for Preparation of
• Himbacine analogs as thrombin receptor antagonists and potential antiplatelet agents
• Trisulfonated calixarene upper-rim sulfonamido and their complexation with trimethyllysine epigenetic mark
• Antimalarial compounds via Suzuki cross-coupling
• Deoxyuridine derivatives
Molecular Spectra
No Data Available
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References
No Data Available
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