Substance
ID:315279
Names and Identifiers
IUPAC Traditional name
isoquinolin-4-ylboronic acid
IUPAC name
(isoquinolin-4-yl)boronic acid
Synonyms
Isoquinoline-4-boronic acid4-Isoquinolineboronic acid4-异喹啉硼酸Isoquinolin-4-ylboronic acid异喹啉-4-硼酸
Properties
Physical Property
Melting Point
230-234 °C
Safety Information
Risk Statements
36/37/38
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
European Hazard Symbols
Irritant (Xi)GHS Precautionary statements
P261-P305+P351+P338
German water hazard class
3
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Storage Temperature
2-8°C
MSDS Link
GHS Hazard statements
H315-H319-H335
GHS Signal Word
Warning
Safety Statements
26
Product Information
Empirical Formula (Hill Notation)
C9H8BNO2
Molecule Details
General description
May contain varying amounts of anhydride
Packaging
1, 5 g in glass bottle
Application
Reactant for:
• Preparation of selective steroid-11β-hydroxylase (CYP11B1) inhibitors for treatment of cortisol dependent diseases1
• Preparation of tetrabutylammonium trifluoroborates2
• Preparation of heteroaryl substituted tetrahydropyrroloijquinolinone derivatives as aldosterone synthase inhibitors3
• Synthesis of aminoarylpyridazines as selective CB2 agonists for treatment of inflammatory pain4
• Preparation of acyl substituted indoles via palladium-catalyzed domino coupling/carbonylation/Suzuki coupling of dibromoethenylanilines5
• Synthesis of antagonists of bacterial quorum sensing6
• Preparation of potassium heteroaryl trifluoroborates from boronic acids and their use as coupling partners with various aryl and heteroaryl halides in Suzuki-Miyaura cross-coupling reactions7
May contain varying amounts of anhydride
Packaging
1, 5 g in glass bottle
Application
Reactant for:
• Preparation of selective steroid-11β-hydroxylase (CYP11B1) inhibitors for treatment of cortisol dependent diseases1
• Preparation of tetrabutylammonium trifluoroborates2
• Preparation of heteroaryl substituted tetrahydropyrroloijquinolinone derivatives as aldosterone synthase inhibitors3
• Synthesis of aminoarylpyridazines as selective CB2 agonists for treatment of inflammatory pain4
• Preparation of acyl substituted indoles via palladium-catalyzed domino coupling/carbonylation/Suzuki coupling of dibromoethenylanilines5
• Synthesis of antagonists of bacterial quorum sensing6
• Preparation of potassium heteroaryl trifluoroborates from boronic acids and their use as coupling partners with various aryl and heteroaryl halides in Suzuki-Miyaura cross-coupling reactions7
Molecular Spectra
No Data Available
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References
No Data Available
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