Substance

ID:315025

Names and Identifiers
IUPAC name
1H-indol-6-amine
IUPAC Traditional name
1H-indol-6-amine
Synonyms
6-AminoindoleIndol-6-ylamine6-氨基吲哚NSC 82379
Registration numbers
CAS Number
MDL Number
PubChem SID
Properties
Safety Information
Storage Temperature
-20°C
German water hazard class
3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
22-36/37/38
GHS Signal Word
Warning
Safety Statements
26-36
GHS Precautionary statements
P261-P305+P351+P338
GHS Hazard statements
H302-H315-H319-H335
MSDS Link
GHS Pictograms
GHS07
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Harmful Harmful (Xn)
Physical Property
Melting Point
75-79 °C
Product Information
Empirical Formula (Hill Notation)
C8H8N2
Purity
97%
Molecule Details
Packaging
1, 5 g in glass bottle
Application
Reactant for preparation of:
• Inhibitors of mammalian target of rapamycin (mTOR ) protein1
• Inhibitors of the AcrAB-TolC efflux pump2
• Inhibitors of Gli1-mediated transcription in the Hedgehog pathway3
• Potent DNA-topoisomerase II poisons and anti-MDR agents4
• Protein kinase C θ (PKCθ) inhibitors5
• Piperidine carboxamide as transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists6
• Potent and selective blockers of the Nav1.8 sodium channel as potential analgesics for the treatment of neuropathic and inflammatory pain7
• 5,6-fused heteroaromatic ureas as TRPV1 antagonists8
• Allosteric enhancers of the A3 adenosine receptor9
• Human liver glycogen phosphorylase (HLGP) inhibitors for the treatment of type 2 diabetes10
Molecular Spectra
No Data Available
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References
No Data Available
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