Substance
ID:314321
Names and Identifiers
IUPAC name
N-[(ethoxycarbonyl)imino]ethoxyformamide
IUPAC Traditional name
diethyl azodicarboxylate
Synonyms
NSC 679015Diethoxycarbonyldiazene solutionNSC 3474偶氮二甲酸二乙酯 溶液1,2-Ethoxycarbonyl diazene solutionUnifoam AZ-AE 200DEADDiethyl azodiformate solutionDiethyl azodicarboxylate solution
Registration numbers
CAS Number
MDL Number
Beilstein Number
PubChem SID
Properties
Safety Information
European Hazard Symbols
Harmful (Xn)GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Flammable gases, category 1
Flammable aerosols, categories 1,2
Flammable liquids, categories 1,2,3
Self-reactive substances and mixtures, Types B,C,D,E,F
Pyrophoric liquids, category 1
Pyrophoric solids, category 1
Self-heating substances and mixtures
Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3
Organic peroxides, Types B,C,D,E,F
Safety Statements
26-36/37-62
GHS Signal Word
Danger
UN Number
3379
GHS Hazard statements
H226-H304-H315-H319-H335-H336-H361d-H373
Personal Protective Equipment
Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Risk Statements
63-10-20-36/37/38-48/20-65
RID/ADR
UN 3379 3/PG 1
MSDS Link
GHS Precautionary statements
P261-P281-P301+P310-P305+P351+P338-P331
Packing Group
1
Storage Temperature
2-8°C
Hazard Class
3
German water hazard class
3
Physical Property
Refractive Index
n20/D 1.47
Flash Point
105.8 °F
41 °C
Product Information
Linear Formula
C2H5OCON=NCOOC2H5
Concentration
~40% in toluene (H-NMR)
Grade
purum
Molecule Details
Other Notes
Reagent used in the Mitsunobu reaction, reviews9,10,11
Application
Reactant for preparation of:
• Immunostimulants α-Galactosylceramides1
• Cellotriose and cellotetraose analogues as transition state mimics for mechanistic studies of cellulases2
• Bisubstrate inhibitors with molecular recognition at the active site of catechol-O-methyltransferase3
• Derivatives of F200 and S383 with cannabinoid CB1 receptor binding activities4
• Aza-β-lactams via NHC-catalyzed [2 + 2] cycloaddition with ketenes5Reagent for:
• Annulation of N-protected imines6
• α-thiocyanation of enolizable ketones with ammonium thiocyanate7
• Diels-Alder reactions8
Reagent used in the Mitsunobu reaction, reviews9,10,11
Application
Reactant for preparation of:
• Immunostimulants α-Galactosylceramides1
• Cellotriose and cellotetraose analogues as transition state mimics for mechanistic studies of cellulases2
• Bisubstrate inhibitors with molecular recognition at the active site of catechol-O-methyltransferase3
• Derivatives of F200 and S383 with cannabinoid CB1 receptor binding activities4
• Aza-β-lactams via NHC-catalyzed [2 + 2] cycloaddition with ketenes5Reagent for:
• Annulation of N-protected imines6
• α-thiocyanation of enolizable ketones with ammonium thiocyanate7
• Diels-Alder reactions8
Molecular Spectra
No Data Available
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References
No Data Available
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