Substance
ID:313784
Names and Identifiers
IUPAC Traditional name
griseofulvin
Synonyms
(2S)-trans-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro(benzofuran-2[3H],1′-[2]cyclohexene)-3,4′-dione(+)-Griseofulvin(+)-灰黄霉素(2S)-反式-7-氯-2′,4,6-三甲氧基-6′-甲基螺(苯并呋喃-2[3H],1′-[2]环己烯)-3,4′-二酮Griseofulvin灰黄霉素
IUPAC name
(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione
Properties
Physical Property
Melting Point
218-220 °C(lit.)
Optical Rotation
[α]17/D +370°, c = 1 in chloroform
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Risk Statements
60-61-40-43
RTECS
WG9800000
Safety Statements
22-36/37/39-45
GHS Hazard statements
H317-H351-H360
MSDS Link
GHS Precautionary statements
P201-P280-P308+P313
German water hazard class
3
GHS Signal Word
Danger
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
European Hazard Symbols
Toxic (T)Product Information
Empirical Formula (Hill Notation)
C17H17ClO6
Molecule Details
Features and Benefits
Antimitotic.
Antimitotic.
Molecular Spectra
No Data Available
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References
No Data Available
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