Substance
ID:312312
Names and Identifiers
Synonyms
反式-脱氢雄甾酮普拉睾酮去氢表雄酮脱氢异雄酮雄素-5-烯-3β-醇-17-酮DHEA3β-羟基-5-雄烯-17-酮trans-Dehydroandrosterone5-Androsten-3β-ol-17-onePrasteroneDehydroepiandrosteroneDehydroisoandrosterone3β-Hydroxy-5-androsten-17-one
IUPAC Traditional name
dehydroepiandrosterone
IUPAC name
(1S,2R,5S,10R,11S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-7-en-14-one
Registration numbers
Beilstein Number
CAS Number
MDL Number
EC Number
Properties
Product Information
Purity
97%
Empirical Formula (Hill Notation)
C19H28O2
Safety Information
GHS Hazard statements
H315-H319-H335
Drug Control
regulated under CDSA - not available from Sigma-Aldrich Canada
GHS Signal Word
Warning
Safety Statements
26-36
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
RTECS
BV8396000
MSDS Link
Risk Statements
36/37/38
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
German water hazard class
2
European Hazard Symbols
Irritant (Xi)GHS Precautionary statements
P261-P305+P351+P338
Physical Property
Melting Point
149-151 °C(lit.)
Optical Rotation
[α]25/D +13.0°, c = 1 in ethanol
Molecule Details
Biochem/physiol Actions
Negative modulator of GABAA receptors. Steroid secreted by the adrenal gland with both estrogenic and androgenic properties. Its conversion to 5-androstenediol, a potent estrogen, enhances the growth and survival of estrogen-sensitive breast tumors. At high but physiologically valid concentrations, DHEA inhibits proliferation of chromaffin progenitor cells and induces dopaminergic differentiation.1
Negative modulator of GABAA receptors. Steroid secreted by the adrenal gland with both estrogenic and androgenic properties. Its conversion to 5-androstenediol, a potent estrogen, enhances the growth and survival of estrogen-sensitive breast tumors. At high but physiologically valid concentrations, DHEA inhibits proliferation of chromaffin progenitor cells and induces dopaminergic differentiation.1
Molecular Spectra
No Data Available
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References
No Data Available
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