Substance
ID:311944
Names and Identifiers
IUPAC Traditional name
zidovudine
IUPAC name
1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
Synonyms
azidothymidine3′-Azido-3′-deoxythymidine齐多夫定3′-叠氮-3′-脱氧胸苷ZDVZidovudineAZT叠氮胸苷
Properties
Safety Information
European Hazard Symbols
Harmful (Xn)GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
36/37/39-45
GHS Signal Word
Warning
GHS Hazard statements
H351
MSDS Link
RTECS
XP2072000
GHS Precautionary statements
P281
Risk Statements
40
German water hazard class
3
Product Information
Purity
98%
Empirical Formula (Hill Notation)
C10H13N5O4
Physical Property
Melting Point
113-115 °C(lit.)
Optical Rotation
[α]20/D +47°, c = 0.5 in H2O
Molecule Details
Biochem/physiol Actions
Reverse transcriptase inhibitor active against HIV-1 virus.
Reverse transcriptase inhibitor active against HIV-1 virus.
Molecular Spectra
No Data Available
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References
No Data Available
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