Substance
ID:311840
Names and Identifiers
IUPAC Traditional name
histamine dihydrochloride
IUPAC name
2-(1H-imidazol-4-yl)ethan-1-amine dihydrochloride
Synonyms
2-(4-咪唑)乙胺 二盐酸盐Histamine dihydrochloride组胺 二盐酸盐2-(4-Imidazolyl)ethylamine dihydrochloride
Registration numbers
CAS Number
MDL Number
EC Number
Beilstein Number
Properties
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Signal Word
Danger
GHS Precautionary statements
P261-P280-P305+P351+P338-P342+P311
German water hazard class
2
European Hazard Symbols
Harmful (Xn)RTECS
MS1575000
GHS Hazard statements
H315-H317-H319-H334-H335
Risk Statements
36/37/38-42/43
MSDS Link
Safety Statements
22-26-36/37/39-45
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Product Information
Purity
98%
Empirical Formula (Hill Notation)
C5H9N3 · 2HCl
Physical Property
Melting Point
249-252 °C(lit.)
Molecule Details
Biochem/physiol Actions
Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.
Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.
Molecular Spectra
No Data Available
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References
No Data Available
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