Substance
ID:311163
Names and Identifiers
Synonyms
咖啡因1,3,7-三甲基黄嘌呤Caffeine1,3,7-Trimethylxanthine
IUPAC Traditional name
caffeine
IUPAC name
1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Registration numbers
MDL Number
Beilstein Number
CAS Number
EC Number
Flavis Number
PubChem SID
FEMA ID
Council of Europe Number
Properties
Product Information
Grade
Kosher
Halal
NI
anhydrous
Empirical Formula (Hill Notation)
C8H10N4O2
Safety Information
Risk Statements
22
Packing Group
3
RID/ADR
UN 1544 6.1/PG 3
German water hazard class
1
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Signal Word
Warning
RTECS
EV6475000
MSDS Link
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Hazard statements
H302
Hazard Class
6.1
UN Number
1544
Regulation Compliance
FDA 21 CFR (182.1180)
FCC
European Hazard Symbols
Harmful (Xn)Pharmacology Properties
Allergens
no known allergens
Gene Information
human ... ADORA1(134), ADORA2B(136), ADORA3(140), PDE4B(5142)mouse ... Adora2b(11541)rat ... Adora1(29290), Adora2a(25369)
Physical Property
Melting Point
234-236.5 °C(lit.)
Molecule Details
Packaging
1 kg in poly bottle
1 sample in glass bottle
10, 25 kg in fiber drum
Biochem/physiol Actions
A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.
1 kg in poly bottle
1 sample in glass bottle
10, 25 kg in fiber drum
Biochem/physiol Actions
A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.
Molecular Spectra
No Data Available
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References
No Data Available
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