Substance
ID:311149
Names and Identifiers
IUPAC Traditional name
cyclophosphamide hydrate
Synonyms
Cytoxan环磷酰胺 一水合物2-[双(2-氯乙基)氨基]四氢-2H-1,3,2-噁磷-2-氧化物Cyclophosphamide monohydrate2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
IUPAC name
2-[bis(2-chloroethyl)amino]-1,3,2λ5-oxazaphosphinan-2-one hydrate
Registration numbers
CAS Number
Beilstein Number
MDL Number
EC Number
Properties
Product Information
Empirical Formula (Hill Notation)
C7H15Cl2N2O2P · H2O
Purity
≥98%
Physical Property
Melting Point
49-51 °C(lit.)
Flash Point
235.4 °F
113 °C
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Precautionary statements
P201-P301+P310-P308+P313
RTECS
RP6157750
Safety Statements
53-45
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Risk Statements
45-25
German water hazard class
3
Packing Group
3
MSDS Link
European Hazard Symbols
Toxic (T)UN Number
3464
Hazard Class
6.1
GHS Signal Word
Danger
GHS Hazard statements
H301-H350
RID/ADR
UN 3464 6.1/PG 3
Molecule Details
Features and Benefits
Cancer research tool.
Biochem/physiol Actions
Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.
Cancer research tool.
Biochem/physiol Actions
Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.
Molecular Spectra
No Data Available
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References
No Data Available
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