Substance
ID:309454
Names and Identifiers
IUPAC name
(1S,6R,13S)-16,17-dimethoxy-6-(prop-1-en-2-yl)-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one
IUPAC Traditional name
cube root
Synonyms
鱼滕精Rotenone
Registration numbers
CAS Number
Beilstein Number
MDL Number
EC Number
Properties
Product Information
Impurities
<5% dimethyl phthalate (extraction solvent)
Purity
95%
Empirical Formula (Hill Notation)
C23H22O6
Physical Property
Optical Rotation
[α]20/D -115°, c = 1.4 in chloroform
Boiling Point
210-220 °C/0.5 mmHg(lit.)
Melting Point
159-164 °C(lit.)
Safety Information
European Hazard Symbols
Nature polluting (N)
Toxic (T)Hazard Class
6.1
MSDS Link
Safety Statements
22-24/25-36-45-60-61
UN Number
2811
German water hazard class
3
Packing Group
3
Risk Statements
25-36/37/38-50/53
RTECS
DJ2800000
RID/ADR
UN 2811 6.1/PG 3
Molecule Details
Biochem/physiol Actions
Inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone is used to induce a Parkinson-like syndrome as an experimental model in rats.
Inhibitor of mitochondrial electron transport. Neurotoxic agent that can produce a Parkinson-like condition as an animal model for study of etiology and interventions.
Inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone is used to induce a Parkinson-like syndrome as an experimental model in rats.
Inhibitor of mitochondrial electron transport. Neurotoxic agent that can produce a Parkinson-like condition as an animal model for study of etiology and interventions.
Molecular Spectra
No Data Available
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References
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