Substance
ID:309059
Names and Identifiers
IUPAC Traditional name
β-mercaptoethanol
IUPAC name
2-sulfanylethan-1-ol
Synonyms
2-羟基乙硫醇β-巯基乙醇BME硫代乙二醇2-Mercaptoethanol2-巯基乙醇2-HydroxyethylmercaptanThioethylene glycolβ-Mercaptoethanol
Properties
Physical Property
Density
1.114 g/mL at 25 °C(lit.)
Vapor Density
2.69 (vs air)
Vapor Pressure
1 mmHg ( 20 °C)
Flash Point
68 °C
154.4 °F
Refractive Index
n20/D 1.500(lit.)
Boiling Point
157 °C(lit.)
Safety Information
MSDS Link
European Hazard Symbols
Nature polluting (N)
Toxic (T)Safety Statements
26-36/37/39-45-60-61
GHS Pictograms
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
GHS Signal Word
Danger
GHS Hazard statements
H301-H310+H330-H315-H317-H318-H410
Explode Limits
18 %
RID/ADR
UN 2966 6.1/PG 2
Personal Protective Equipment
Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
UN Number
2966
GHS Precautionary statements
P260-P273-P280-P284-P301+P310-P302+P350
Risk Statements
23/24/25-38-41-43-50/53
RTECS
KL5600000
Hazard Class
6.1
Packing Group
2
German water hazard class
3
Product Information
Linear Formula
HSCH2CH2OH
Concentration
14.3 M (pure liquid)
Purity
99%
Molecule Details
Application
BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.
Legal Information
Product of Arkema Inc.
BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.
Legal Information
Product of Arkema Inc.
Molecular Spectra
No Data Available
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References
No Data Available
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