Substance
ID:307405
Names and Identifiers
Synonyms
咖啡因1,3,7-三甲基黄嘌呤Caffeine1,3,7-Trimethylxanthine
IUPAC Traditional name
caffeine
IUPAC name
1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Properties
Physical Property
Melting Point
234-236.5 °C(lit.)
Product Information
Grade
TraceCERT®
certified reference material
Empirical Formula (Hill Notation)
C8H10N4O2
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
MSDS Link
RTECS
EV6475000
GHS Signal Word
Warning
GHS Hazard statements
H302
European Hazard Symbols
Harmful (Xn)Risk Statements
22
German water hazard class
1
Molecule Details
General description
Certified content by quantitative NMR incl. uncertainty and expiry are given in the certificate.Download your certificate at: http://www.sigma-aldrich.com.
Biochem/physiol Actions
A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.
Legal Information
TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC
Certified content by quantitative NMR incl. uncertainty and expiry are given in the certificate.Download your certificate at: http://www.sigma-aldrich.com.
Biochem/physiol Actions
A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.
Legal Information
TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC
Molecular Spectra
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References
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