Substance
ID:272
Names and Identifiers
IUPAC name
ethyl 3-methyl-2-sulfanylidene-2,3-dihydro-1H-imidazole-1-carboxylate
IUPAC Traditional name
carbimazole
Synonyms
CarbimazoleCarbimazolum [INN-Latin]CarbethoxymethimazoleCarbimazolAthyromazoleCarbimazol [INN-Spanish, French]Carbinazole
Brand Name
Neo-MercazoleAtirozidinaBasolestCarbimazol SpofaNeo-TireolCG1CarbotiroidMertiranNeo-ThyreostatNeomercazoleTyrazol
Properties
Physical Property
Hydrophobicity(logP)
0.4
Molecule Details
Drug Groups
approved
Description
An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity. [PubChem]
Indication
For the treatment of hyperthyroidism and thyrotoxicosis. It is also used to prepare patients for thyroidectomy.
Pharmacology
Carbimazole is a carbethoxy derivative of methimazole. Its antithyroid action is due to its conversion to methimazole after absorption. It is used to treat hyperthyroidism and thyrotoxicosis.
Affected Organisms
Humans and other mammals
Protein Binding
85%
External Links
Molecular Spectra
No Data Available
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References
No Data Available
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