Substance
ID:23
Names and Identifiers
Synonyms
LuteineXanthophyllVegetable luteinLutein esterCarotenoidAll-trans-(+)-XanthophyllPhylloxanthintrans-LuteinLutein4,5-Didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diolbeta,epsilon-Carotene-3,3'-diolVegetable luteol(3R,3'R,6S)-4,5-Didehydro-5,6-Dihydro-Beta,Beta-Carotene-3,3'-DiolAll-trans-Luteinall-trans-Xanthophyll(3R,3'R)-Beta,Beta-Carotene-3,3'-Diol, Lutein(3R,3'R,6'R)-Lutein
IUPAC Traditional name
xanthophyll
Brand Name
Bo-Xan
IUPAC name
4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-(4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]-3,5,5-trimethylcyclohex-2-en-1-ol
Properties
Physical Property
Hydrophobicity(logP)
7.9
Solubility
Insoluble
Molecule Details
Drug Groups
approved; nutraceutical
Description
Xanthophylls are yellow pigments from the carotenoid group that are widespread in nature. They are present in egg yolk, algae, and petals of yellow flowers, among other sources. The xanthophylls include lutein, zeaxanthin, neoxanthin, violaxanthin, and α- and β-cryptoxanthin, of which lutein is the primary ingested one.
Indication
Xanthophylls are taken for nutritional supplementation, and also for treating dietary shortage or imbalance.
Pharmacology
Lutein was found to be present in a concentrated area of the macula, a small area of the retina responsible for central vision. The hypothesis for the natural concentration is that lutein helps protect from oxidative stress and high-energy light. Several studies show that an increase in macula pigmentation decreases the risk for eye diseases such as Age-related Macular Degeneration (AMD).
Affected Organisms
Humans and other mammals
References
External Links
Molecular Spectra
No Data Available
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