Substance

ID:1861678

Names and Identifiers
IUPAC name
4-[2-(6-methylpyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide
Synonyms
LY-2157299LY 2157299LY2157299
International Nonproprietary Name (INN)
galunisertibgalunisertibum
IUPAC Traditional name
galunisertib
Registration numbers
PubChem CID
10090485
CAS Number
700874-72-2
Reaxys Registry
14275134
BKMS React Database
146937217787
BRENDA Database
2.7.11.30
BRENDA Ligand Database
146937217787
CompTox Database
DTXSID00220362
SureChEMBL Database
SCHEMBL12922153
Wikipedia Title
Galunisertib
BindingDB Database
50015640
KEGG DRUG Database
D10437
CHEBI ID
CHEBI:137064
PubChem SID
85336792
Properties
No Data Available
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Molecule Details
A pyrrolopyrazole that is 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole which is substituted at positions 2 and 3 by 6-methylpyridin-2-yl and 6-(aminocarbonyl)quinolin-4-yl groups, respectively. A Transforming growth factor-betaRI (TGF-betaRI) kinase inhibitor, it blocks TGF-beta-mediated tumor growth in glioblastoma.
Molecular Spectra
No Data Available
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References
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