Substance

ID:1855097

Names and Identifiers
IUPAC Traditional name
panobinostat
IUPAC name
(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide
Synonyms
panobinostatLBH 589LBH589
International Nonproprietary Name (INN)
panobinostat
Registration numbers
CAS Number
PubChem CID
Reaxys Registry
BKMS React Database
BRENDA Ligand Database
CompTox Database
Protein Data Bank
SureChEMBL Database
Wikipedia Title
Drug Central Database
BindingDB Database
KEGG DRUG Database
ArrayExpress (Gene Expression Altlas)
CHEBI ID
PubChem SID
Properties
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Molecule Details
A hydroxamic acid obtained by formal condensation of the carboxy group of (2E)-3-[4-({[2-(2-methylindol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enoic acid with the amino group of hydroxylamine. A histone deacetylase inhibitor used (as its lactate salt) in combination with bortezomib and dexamethasone for the treatment of multiple myeloma.
Molecular Spectra
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References
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