Substance
ID:184736
Names and Identifiers
IUPAC name
6-bromo-5-(methylamino)-2-{[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylic acid
Synonyms
4-Bromo-calcium Ionophore A231874-Bromo-A231874-Bromo-calcimycin
IUPAC Traditional name
6-bromo-5-(methylamino)-2-{[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylic acid
Properties
Physical Property
Solubility
ethanol: soluble20 mg/mL
DMSO: soluble
Apperance
yellow powder
Safety Information
European Hazard Symbols
Harmful (Xn)GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Signal Word
Warning
GHS Precautionary statements
P261-P280-P305+P351+P338
Risk Statements
20/21/22-36/37/38
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
German water hazard class
3
Safety Statements
26-36/37
GHS Hazard statements
H302-H312-H315-H319-H332-H335
Storage Temperature
2-8°C
Molecule Details
Application
Nonfluorescent Ca2+ ionophore that can be used to calibrate the quantitation of cytoplasmic free Ca2+ with fluorescent probes.
Biochem/physiol Actions
Ca2+ ionophore that is used to potentiate responses to NMDA, but not quisqualate.
Other Notes
Analog of calcium ionophore A23187
Nonfluorescent Ca2+ ionophore that can be used to calibrate the quantitation of cytoplasmic free Ca2+ with fluorescent probes.
Biochem/physiol Actions
Ca2+ ionophore that is used to potentiate responses to NMDA, but not quisqualate.
Other Notes
Analog of calcium ionophore A23187
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data