Substance
ID:184725
Names and Identifiers
IUPAC name
6-(2-{4-[(4-fluorophenyl)(phenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-1H,5H-imidazo[1,2-a]pyrimidin-5-one
Synonyms
6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidin-yl]ethyl]-7-methyl-5H-thiazolo-[3,2-a]-pyrimidin-5-oneR59022Diacylglycerol Kinase Inhibitor I
IUPAC Traditional name
6-(2-{4-[(4-fluorophenyl)(phenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-1H-imidazo[1,2-a]pyrimidin-5-one
Properties
Physical Property
Apperance
pale yellow solid
Solubility
ethanol: soluble
ethyl acetate: soluble
0.1 M NaOH: slightly soluble
DMSO: soluble
H2O: insoluble
0.1 M HCl: slightly soluble
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class
3
Storage Temperature
-20°C
Molecule Details
Biochem/physiol Actions
Diacylglycerol kinase inhibitor. Inhibits formation of [38P]1-Oleoxyl-2-acetylglyceryl-3-phosphoric acid (OAPA) in red blood cell membranes: IC50 = 3.3 μM.
Diacylglycerol kinase inhibitor. Inhibits formation of [38P]1-Oleoxyl-2-acetylglyceryl-3-phosphoric acid (OAPA) in red blood cell membranes: IC50 = 3.3 μM.
Molecular Spectra
No Data Available
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References
No Data Available
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