Substance
ID:184657
Names and Identifiers
Synonyms
[D-pGlu1, D-Phe2, D-Trp3,6]-LH-RH
IUPAC Traditional name
(2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-(carbamoylmethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2R)-3-(1H-indol-3-yl)-2-[(2R)-2-{[(2R)-5-oxopyrrolidin-2-yl]formamido}-3-phenylpropanamido]propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-(1H-indol-3-yl)propanamido]-4-methylpentanamide
IUPAC name
(2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2R)-3-(1H-indol-3-yl)-2-[(2R)-2-{[(2R)-5-oxopyrrolidin-2-yl]formamido}-3-phenylpropanamido]propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-(1H-indol-3-yl)propanamido]-4-methylpentanamide
Properties
Safety Information
Storage Temperature
-20°C
Risk Statements
60
GHS Hazard statements
H360
German water hazard class
3
GHS Signal Word
Danger
European Hazard Symbols
Toxic (T)GHS Precautionary statements
P201-P308+P313
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Safety Statements
53-22-36/37/39-45
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Product Information
Purity
≥97% (HPLC)
Molecule Details
Amino Acid Sequence
D-pGlu-D-Phe-D-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2
Biochem/physiol Actions
Substance P antagonist; inhibits spinal cord vasomotor responses
D-pGlu-D-Phe-D-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2
Biochem/physiol Actions
Substance P antagonist; inhibits spinal cord vasomotor responses
Molecular Spectra
No Data Available
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References
No Data Available
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