Substance
ID:184627
Names and Identifiers
Synonyms
m-AMSA4-(9-Acridinylamino)-N-(methanesulfonyl)-m-anisidine hydrochlorideAmsacrine hydrochloride
IUPAC Traditional name
amsacrine hydrochloride
IUPAC name
N-{4-[(acridin-9-yl)amino]-3-methoxyphenyl}methanesulfonamide hydrochloride
Properties
Physical Property
Solubility
30% ethanol: soluble4 mg/mL
DMSO: soluble10 mg/mL (with heat and sonication)
Melting Point
197-199 °C(lit.)
Apperance
red to brown powder
Safety Information
RID/ADR
UN 2811 6.1/PG 3
UN Number
2811
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Hazard statements
H301-H315-H319-H335
Risk Statements
25-36/37/38
Hazard Class
6.1
Packing Group
3
German water hazard class
3
GHS Precautionary statements
P261-P301+P310-P305+P351+P338
Safety Statements
26-45
European Hazard Symbols
Toxic (T)GHS Signal Word
Danger
RTECS
PB1081000
Pharmacology Properties
Gene Information
human ... TOP2A(7153), TOP2B(7155)
Product Information
Purity
≥98% (TLC)
Molecule Details
Biochem/physiol Actions
Amsacrine hydrochloride is a DNA topoisomerase II inhibitor.
Amsacrine hydrochloride is a DNA topoisomerase II inhibitor.
Molecular Spectra
No Data Available
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References
No Data Available
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