Substance
ID:184516
Names and Identifiers
IUPAC name
N-[2-(diethylamino)ethyl]-4-acetamidobenzamide hydrochloride
Synonyms
NAPAN-Acetylprocainamide hydrochlorideN-乙酰普鲁卡因胺 盐酸盐N-乙酰普卡胺 盐酸盐乙酰卡尼 盐酸盐
IUPAC Traditional name
NAPA hydrochloride
Properties
Product Information
Purity
≥99% (HPLC)
Physical Property
Solubility
H2O: soluble50 mg/mL
Apperance
powder
Melting Point
184-186 °C(lit.)
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class
3
Storage Temperature
-20°C
Molecule Details
Application
N-Acetylprocainamide hydrochloride is a class III antiarrhythmic compound. N-Acetylprocainamide hydrochloride has been used in a study to determine the disposition of procainamide and N-acetylprocainamide in protein-calorie malnutrition. N-Acetylprocainamide hydrochloride has also been used to study pharmacokinetics of procainamide and N-acetylprocainamide in rats.
Biochem/physiol Actions
III 类抗心律失常药。通过降低延时的外向钾电流、稍微降低钙电流以及稍微抑制内向整流钾电流来增大动作电位的持续时间。这是普鲁卡因胺的活性代谢物，不会导致全身性红斑狼疮。
N-Acetylprocainamide hydrochloride is a class III antiarrhythmic compound. N-Acetylprocainamide hydrochloride has been used in a study to determine the disposition of procainamide and N-acetylprocainamide in protein-calorie malnutrition. N-Acetylprocainamide hydrochloride has also been used to study pharmacokinetics of procainamide and N-acetylprocainamide in rats.
Biochem/physiol Actions
III 类抗心律失常药。通过降低延时的外向钾电流、稍微降低钙电流以及稍微抑制内向整流钾电流来增大动作电位的持续时间。这是普鲁卡因胺的活性代谢物，不会导致全身性红斑狼疮。
Molecular Spectra
No Data Available
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References
No Data Available
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