Substance
ID:184502
Names and Identifiers
IUPAC Traditional name
clomipramine hydrochloride
Synonyms
3-Chloro-10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochlorideAnafranil hydrochlorideClomipramine hydrochloride
IUPAC name
(3-{14-chloro-2-azatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)dimethylamine hydrochloride
Properties
Product Information
Purity
≥98% (HPLC)
Pharmacology Properties
Gene Information
human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)
Safety Information
GHS Precautionary statements
P261-P280-P305+P351+P338
Safety Statements
13-20/21-22-24/25-26-28-36/37/39-38-62
GHS Signal Word
Warning
RTECS
HN9055000
GHS Hazard statements
H302-H312-H315-H319-H332-H335
European Hazard Symbols
Harmful (Xn)Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
20/21/22-36/37/38
German water hazard class
3
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Physical Property
Solubility
H2O: soluble25 mg/mL
0.1 M HCl: soluble
Apperance
white to off-white powder
Molecule Details
Biochem/physiol Actions
Tricyclic antidepressant; inhibits serotonin and norepinephrine transporters.
Tricyclic antidepressant; inhibits serotonin and norepinephrine transporters.
Molecular Spectra
No Data Available
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References
No Data Available
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