Substance
ID:184486
Names and Identifiers
IUPAC name
N-{4-[(4-nitrophenyl)sulfamoyl]phenyl}acetamide
IUPAC Traditional name
sulfanitran
Synonyms
N4-乙酰基-N1-(4-硝基苯)磺胺Sulfanitran磺胺硝苯
Registration numbers
CAS Number
MDL Number
Beilstein Number
PubChem SID
Properties
Safety Information
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class
3
Product Information
Purity
~85%
Molecule Details
Application
Sulfanitran is used to stimulate MRP2. It is used to stimulate the MRP2-mediated transport of lipophilic amphipathic drugs1. It is used to study the efflux of chemotherapeutics in tumor cell lines1.
Biochem/physiol Actions
Sulfanitran stimulates the ATP binding cassette family transporter multidrug resistance protein 2 (MRP2). Sulfanitran increases the affinity of MRP2 for estradiol-17-β-D-glucuronide2. It stimulates the vectorial transport of saquinavir, a MRP2 substrate, across polarized MDCKII monolayers2.
Sulfanitran is used to stimulate MRP2. It is used to stimulate the MRP2-mediated transport of lipophilic amphipathic drugs1. It is used to study the efflux of chemotherapeutics in tumor cell lines1.
Biochem/physiol Actions
Sulfanitran stimulates the ATP binding cassette family transporter multidrug resistance protein 2 (MRP2). Sulfanitran increases the affinity of MRP2 for estradiol-17-β-D-glucuronide2. It stimulates the vectorial transport of saquinavir, a MRP2 substrate, across polarized MDCKII monolayers2.
Molecular Spectra
No Data Available
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References
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