Substance
ID:184444
Names and Identifiers
IUPAC Traditional name
triphosphate, guanosine; tris(tris buffer)
IUPAC name
({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid; tris(2-amino-2-(hydroxymethyl)propane-1,3-diol)
Synonyms
GTPGuanosine 5′-triphosphate tris salt
Registration numbers
CAS Number
Properties
Safety Information
Safety Statements
22-26-36-45
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Hazard statements
H301-H311-H315-H319-H331-H335
European Hazard Symbols
Toxic (T)GHS Precautionary statements
P261-P280-P301+P310-P305+P351+P338-P311
GHS Signal Word
Danger
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Risk Statements
23/24/25-36/37/38
Storage Temperature
-20°C
German water hazard class
3
Product Information
Shipped in
dry ice
Purity
~95% (HPLC)
Physical Property
Apperance
white powder
Solubility
H2O: soluble50 mg/mL
Molecule Details
Biochem/physiol Actions
GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
Preparation Note
Prepared from Catalog No. G8877.
GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
Preparation Note
Prepared from Catalog No. G8877.
Molecular Spectra
No Data Available
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References
No Data Available
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