Substance

ID:184433

Nigericin sodium salt

Names and Identifiers
Synonyms
Antibiotic X464Helexin CPolyetherin ANigericin sodium saltAntibiotic K178Azalomycin M
IUPAC name
sodium (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl}-3-methyloxan-2-yl]propanoate
IUPAC Traditional name
sodium (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl}-3-methyloxan-2-yl]propanoate
Registration numbers
CAS Number
Beilstein Number
PubChem SID
MDL Number
Properties
Safety Information
German water hazard class
3
GHS Hazard statements
H301-H315-H319-H335
European Hazard Symbols
Toxic Toxic (T)
GHS Precautionary statements
P261-P301+P310-P305+P351+P338
RID/ADR
UN 3462 6.1/PG 3
Safety Statements
26-36/37/39-45
GHS Signal Word
Danger
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Risk Statements
25-36/37/38
Storage Temperature
2-8°C
Packing Group
3
RTECS
QT6840000
GHS Pictograms
GHS06
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Hazard Class
6.1
UN Number
3462
Product Information
Purity
≥98% (TLC)
Quality Level
PREMIUM
Biological Source
from Streptomyces hygroscopicus
Molecule Details
Biochem/physiol Actions
Ionophore which disrupts membrane potential and stimulates ATPase activity in mitochondria.
Polyether ionophore which disrupts membrane potential and stimulates ATPase activity in mitochondria. Ion selectivity is K+> Rb+≥ Cs+>> Na+.
Other Notes
As ion-selective electrode - an efficient K+-carrier.1,2
Molecular Spectra
No Data Available
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References
No Data Available
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