Substance
ID:184357
Names and Identifiers
IUPAC Traditional name
hydrocortisone
IUPAC name
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
Synonyms
氢化皮质酮氢化可的松氢化泼尼松龙皮质醇Hydrocortisone11β,17α,21-三羟基孕甾-4-烯-3,20-二酮17-羟基皮质甾酮4-孕烯-11β,17α,21-三醇-3,20-二酮
Registration numbers
EC Number
PubChem SID
CAS Number
MDL Number
Beilstein Number
Properties
Safety Information
European Hazard Symbols
Harmful (Xn)Risk Statements
63
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
36/37
GHS Signal Word
Warning
GHS Hazard statements
H361
German water hazard class
3
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Precautionary statements
P281
RTECS
GM8925000
Product Information
Quality Level
PREMIUM
Suitability
meets USP testing specifications
Potency
0.004-0.005 μg/mL
Pharmacology Properties
Gene Information
human ... ABCB1(5243), CYP3A4(1576), SERPINA6(866)mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126)rat ... Ar(24208), Nr3c1(24413)
Physical Property
Melting Point
211-214 °C(lit.)
Molecule Details
Physical form
室温下为粉末状；分成小份冻存，以避免使用时反复冷冻/解冻
Biochem/physiol Actions
肾上腺皮质分泌的原发性糖皮质激素。消炎效果是皮质酮的三倍，但 Na2+ 保留性能比皮质酮低。
室温下为粉末状；分成小份冻存，以避免使用时反复冷冻/解冻
Biochem/physiol Actions
肾上腺皮质分泌的原发性糖皮质激素。消炎效果是皮质酮的三倍，但 Na2+ 保留性能比皮质酮低。
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data