Substance
ID:184329
Names and Identifiers
IUPAC name
4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol
IUPAC Traditional name
estrogen
Synonyms
DES(E)-3,4-双(4-羟苯基)3-亚己基Diethylstilbestrol乙芪酚己烯雌酚
Registration numbers
Beilstein Number
EC Number
CAS Number
MDL Number
PubChem SID
Properties
Safety Information
GHS Signal Word
Danger
GHS Hazard statements
H315-H319-H335-H350-H360-H410
Risk Statements
45-61-36/37/38-51/53
Safety Statements
53-36/37/39-45-60-61
GHS Precautionary statements
P201-P261-P273-P305+P351+P338-P308+P313-P501
UN Number
3077
GHS Pictograms
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Nature polluting (N)
Toxic (T)RTECS
WJ5600000
German water hazard class
3
RID/ADR
UN 3077 9/PG 3
Hazard Class
9
Packing Group
3
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Product Information
Purity
≥99% (HPLC)
Pharmacology Properties
Gene Information
human ... ESR1(2099), ESR2(2100), ESRRG(2104)mouse ... Esr1(13982)rat ... Ar(24208), Esr1(24890)
Molecule Details
Biochem/physiol Actions
Diethylstilbestrol is a synthetic estrogen with carcinogenic properties. Causes renal clear-cell carcinoma in Syrian hamster. In humans it causes increased risk of breast cancer, clear cell adenocarcinoma (CCA) of the vagina and cervix, and reproductive anomalies. Used in the treatment of prostate cancer to block the production of testosterone.
Diethylstilbestrol is a synthetic estrogen with carcinogenic properties. Causes renal clear-cell carcinoma in Syrian hamster. In humans it causes increased risk of breast cancer, clear cell adenocarcinoma (CCA) of the vagina and cervix, and reproductive anomalies. Used in the treatment of prostate cancer to block the production of testosterone.
Molecular Spectra
No Data Available
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References
No Data Available
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