Substance

ID:184326

4α-Phorbol 12,13-didecanoate

Names and Identifiers
Synonyms
4α-Phorbol 12-13-dicaprinate4α-Phorbol 12,13-didecanoate4αPDD
IUPAC Traditional name
(1S,2S,6S,10S,11R,13S,14R,15R)-14-(decanoyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dien-13-yl decanoate
IUPAC name
(1S,2S,6S,10S,11R,13S,14R,15R)-14-(decanoyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dien-13-yl decanoate
Registration numbers
Beilstein Number
CAS Number
PubChem SID
MDL Number
Properties
Safety Information
European Hazard Symbols
Highly toxic Highly toxic (T+)
GHS Precautionary statements
P260-P264-P280-P284-P301+P310-P302+P350
Storage Temperature
-20°C
Packing Group
2
RID/ADR
UN 2811 6.1/PG 2
Risk Statements
26/27/28-40-43
GHS Pictograms
GHS06
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Hazard Class
6.1
GHS Signal Word
Danger
UN Number
2811
German water hazard class
3
GHS Hazard statements
H300-H310-H330-H334-H351
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Safety Statements
36/37/39-45
Physical Property
Solubility
methanol: soluble
ethanol: soluble
DMSO: soluble
Apperance
white solid
Molecule Details
Application
Phorbol that is not biologically active, can be used as a negative control.
Biochem/physiol Actions
Skin tumor promoter in experimental animal model.1
Caution
Photosensitive
Reconstitution
Stock solution cannot be made in aqueous media; dissolve in a water-miscible organic solvent before dilution to working concentrations in aqueous media.
Molecular Spectra
No Data Available
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References
No Data Available
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