Substance
ID:184275
Names and Identifiers
IUPAC name
2-(1H-imidazol-4-yl)ethan-1-amine
IUPAC Traditional name
histamine
Synonyms
组胺2-(4-咪唑基)乙胺Histamine
Registration numbers
EC Number
Beilstein Number
CAS Number
PubChem SID
MDL Number
Properties
Physical Property
Boiling Point
167 °C/0.8 mmHg(lit.)
Melting Point
83-84 °C(lit.)
Safety Information
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Risk Statements
22-36/37/38-42/43
Storage Temperature
-20°C
GHS Signal Word
Danger
European Hazard Symbols
Harmful (Xn)Hazard Class
6.1
UN Number
2811
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements
P261-P280-P301+P310-P305+P351+P338-P342+P311
RTECS
MS1050000
Safety Statements
22-26-36/37
RID/ADR
UN 2811 6.1/PG 3
Packing Group
3
GHS Hazard statements
H301-H315-H317-H319-H334-H335
German water hazard class
3
Pharmacology Properties
Gene Information
human ... CA1(759), CA2(760), HRH1(3269), HRH2(3274), HRH3(11255), HRH4(59340)rat ... Hrh1(24448), Hrh3(85268)
Product Information
Purity
≥97.0%
Molecule Details
包装
1, 5, 25 g in glass bottle
Biochem/physiol Actions
内源性 H1 和 H2 组胺受体激动剂；H1 的活化可以使 Ca2+ 移动；H2 的活化可促进神经元中腺苷酸环化酶的活性；活化一氧化氮合成酶；有效的血管舒张剂。
1, 5, 25 g in glass bottle
Biochem/physiol Actions
内源性 H1 和 H2 组胺受体激动剂；H1 的活化可以使 Ca2+ 移动；H2 的活化可促进神经元中腺苷酸环化酶的活性；活化一氧化氮合成酶；有效的血管舒张剂。
Molecular Spectra
No Data Available
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References
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