Substance
ID:184223
Names and Identifiers
IUPAC Traditional name
progesterone
IUPAC name
(1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
Synonyms
Progesterone孕酮孕烯二酮
Registration numbers
EC Number
Beilstein Number
MDL Number
CAS Number
PubChem SID
Properties
Physical Property
Melting Point
128-132 °C(lit.)
Apperance
powder
Solubility
absolute ethanol: soluble1 mg/mL
Safety Information
European Hazard Symbols
Harmful (Xn)GHS Hazard statements
H351
GHS Precautionary statements
P281
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
RTECS
TW0175000
Safety Statements
36/37
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
German water hazard class
3
Risk Statements
40
GHS Signal Word
Warning
Product Information
Suitability
suitable for cell culture
Description
synthesized from materials derived from plant source
Potency
0.1-20 ng/mL
Pharmacology Properties
Gene Information
human ... ABCB1(5243), AR(367), CYP2C9(1559), EBP(10682), ESR1(2099), ESR2(2100), NR3C1(2908), NR3C2(4306), PGR(5241), SERPINA6(866)mouse ... Esr1(13982)rat ... Ar(24208), Nr3c1(24413), Pgr(25154)
Molecule Details
Application
Use in cell culture applications to study sterol regulation of cell signaling and gene expression.
Other Notes
由卵巢黄体产生的类固醇激素。
Reconstitution
To prepare 20μg/ml stock solution, add 1ml absolute ethanol per mg progesterone, gently swirl to dissolve, add 49ml sterile medium per ml ethanol.
Physical form
powder-RT; stock-frozen in working aliquots, avoid repeated freeze/thaw
Biochem/physiol Actions
诱导子宫内皮细胞的成熟和分泌活动;抑制排卵。孕酮与乳腺癌的病因有关。
Use in cell culture applications to study sterol regulation of cell signaling and gene expression.
Other Notes
由卵巢黄体产生的类固醇激素。
Reconstitution
To prepare 20μg/ml stock solution, add 1ml absolute ethanol per mg progesterone, gently swirl to dissolve, add 49ml sterile medium per ml ethanol.
Physical form
powder-RT; stock-frozen in working aliquots, avoid repeated freeze/thaw
Biochem/physiol Actions
诱导子宫内皮细胞的成熟和分泌活动;抑制排卵。孕酮与乳腺癌的病因有关。
Molecular Spectra
No Data Available
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References
No Data Available
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