Substance
ID:184221
Names and Identifiers
IUPAC Traditional name
progesterone
IUPAC name
(1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
Synonyms
Progesterone孕酮孕烯二酮
Registration numbers
EC Number
Beilstein Number
MDL Number
CAS Number
PubChem SID
Properties
Pharmacology Properties
Gene Information
human ... ABCB1(5243), AR(367), CYP2C9(1559), EBP(10682), ESR1(2099), ESR2(2100), NR3C1(2908), NR3C2(4306), PGR(5241), SERPINA6(866)mouse ... Esr1(13982)rat ... Ar(24208), Nr3c1(24413), Pgr(25154)
Safety Information
GHS Signal Word
Warning
European Hazard Symbols
Harmful (Xn)Risk Statements
40
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Hazard statements
H351
GHS Precautionary statements
P281
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
German water hazard class
3
RTECS
TW0175000
Safety Statements
36/37
Product Information
Description
synthesized from materials derived from plant source
Potency
0.1-20 ng/mL
Suitability
suitable for cell culture
Sterility
γ-irradiated
Physical Property
Melting Point
128-132 °C(lit.)
Apperance
powder
Molecule Details
Application
用于细胞培养，研究细胞信号传导和基因表达的甾醇调控。
Other Notes
由卵巢黄体产生的类固醇激素。
Reconstitution
要制备 20μg/mL 的储存液，可加入 1mL 无水乙醇，温和搅拌使之溶解，再加入 49mL 无菌培养基。
Physical form
室温下为粉末状；分成小份冻存，以避免使用时反复冷冻/解冻
Biochem/physiol Actions
诱导子宫内皮细胞的成熟和分泌活动;抑制排卵。孕酮与乳腺癌的病因有关。
用于细胞培养，研究细胞信号传导和基因表达的甾醇调控。
Other Notes
由卵巢黄体产生的类固醇激素。
Reconstitution
要制备 20μg/mL 的储存液，可加入 1mL 无水乙醇，温和搅拌使之溶解，再加入 49mL 无菌培养基。
Physical form
室温下为粉末状；分成小份冻存，以避免使用时反复冷冻/解冻
Biochem/physiol Actions
诱导子宫内皮细胞的成熟和分泌活动;抑制排卵。孕酮与乳腺癌的病因有关。
Molecular Spectra
No Data Available
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References
No Data Available
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